CHANGES IN THE MRNA EXPRESSION OF GLYCOLYSIS-RELATED ENZYMES OF CANDIDA ALBICANS DURING INHIBITION OF INTRAMITOCHONDRIAL CATABOLISM UNDER ANAEROBIC CONDITION.

Changes in the mRNA expression of glycolysis-related enzymes of Candida albicans during inhibition of intramitochondrial catabolism under anaerobic condition.

Candida albicans can cause two major types of infections: superficial infection and systemic candidiasis.C.albicans infects diverse host niches, owing to a wide range of virulence factors and attributes, such as morphological transitions and phenotypic switching.C.albicans uses glycolysis, followed by alcoholic fermentation or mitochondrial respira

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Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19: Study Protocol for a Retrospective Observational Multicenter Study (SELECT)

BackgroundIn hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely.Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails.In critically ill patients, high-dose corticosteroids are often administered as salvag

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Impacts of fertilization on grassland productivity and water quality across the European Alps under current and warming climate: insights from a mechanistic model

Alpine grasslands sustain local economy by providing fodder for livestock.Intensive fertilization is common to enhance their yields, thus creating negative externalities on water quality that are difficult to evaluate without reliable estimates of nutrient fluxes.We apply a mechanistic ecosystem model, seamlessly integrating land-surface energy bal

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